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Autophagy and the nutritional signaling pathway

Long HE,Shabnam ESLAMFAM,Xi MA,Defa LI

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 3,   Pages 222-230 doi: 10.15302/J-FASE-2016106

Abstract: During the initiation process, the ATG1/ULK1 (unc-51-like kinase 1) and VPS34 (which encodes a classAmino acid and energy starvation mediate autophagy by activating mTORC1 (mammalian target of rapamycinmechanism of autophagy regulated by nutrient signaling especially for the two important complexes, ULK1

Keywords： Autophagy     ULK1 complex     VPS34 complex     AMPK     mTOR     nutrient signaling    

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Devising optimal integration test orders using cost–benefit analysis Research Article

Fanyi MENG, Ying WANG, Hai YU, Zhiliang ZHU,yuhai@mail.neu.edu.cn

Frontiers of Information Technology & Electronic Engineering 2022, Volume 23, Issue 5,   Pages 692-714 doi: 10.1631/FITEE.2100466

Abstract: Integration testing is an integral part of software testing. Prior studies have focused on reducing test cost in generation. However, there are no studies concerning the testing priorities of critical classes when generating s. Such priorities greatly affect testing efficiency. In this study, we propose an effective strategy that considers both test cost and efficiency when generating test orders. According to a series of dynamic execution scenarios, the software is mapped into a multi-layer dynamic execution network (MDEN) model. By analyzing the dynamic structural complexity, an evaluation scheme is proposed to quantify the class testing priority with the defined class risk index. ; is used to perform cycle-breaking operations, satisfying two principles: assigning higher priorities to higher-risk classes and minimizing the total complexity of test stubs. We also present a strategy to evaluate the effectiveness of algorithms by calculating the reduction of software risk during their testing process. Experiment results show that our approach performs better across software of different scales, in comparison with the existing algorithms that aim only to minimize test cost. Finally, we implement a tool, ITOsolution, to help practitioners automatically generate test orders.

Keywords： Integration test order     Cost–     benefit analysis     Probabilistic risk analysis     Complex network    

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Effects of parenteral nutrition with and without GH on the GH/IGF-1 axis after hepatectomy in hepatocellular

CAO Jie, LUO Shimin, LIANG Lijian, LAI Jiaming, CHEN Shanming

Frontiers of Medicine 2007, Volume 1, Issue 3,   Pages 287-293 doi: 10.1007/s11684-007-0055-x

Abstract: Postoperative hepatic insulin-like growth factor-1 (IGF-1) production may be severely disturbed in patientsComplex alterations in the GH/IGF-1 axis are thought to play an important role in the protein catabolism(POD) 1 and 6.Insulin-like growth factor-1 and IGFBP-3 mRNA in the liver tissue was detected by RT-PCR.On POD 6, serum prealbumin, GH, IGF-1, IGFBP-3, hepatic IGF-1 mRNA, IGFBP-3 mRNA and liver Ki67 LI were

Keywords： control     function     production     surgical     Complex    

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Firefly algorithm with division of roles for complex optimal scheduling Research Articles

Jia Zhao, Wenping Chen, Renbin Xiao, Jun Ye,zhaojia925@163.com,chen_9731@163.com,rbxiao@hust.edu.cn,yejun68@sina.com

Frontiers of Information Technology & Electronic Engineering 2021, Volume 22, Issue 10,   Pages 1311-1333 doi: 10.1631/FITEE.2000691

Abstract: A single strategy used in the cannot effectively solve the complex problem.The use of multiple strategies can greatly improve the versatility of the algorithm for complex optimization

Keywords： 萤火虫算法；角色分工；柯西突变；精英邻域搜索；优化调度    

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Deep learning based wavefront sensor for complex wavefront detection in adaptive optical microscopes Research Articles

Shuwen Hu, Lejia Hu, Wei Gong, Zhenghan Li, Ke Si,weigong@zju.edu.cn,kesi@zju.edu.cn

Frontiers of Information Technology & Electronic Engineering 2021, Volume 22, Issue 10,   Pages 1277-1288 doi: 10.1631/FITEE.2000422

Abstract: However, the distorted spots induced by the complex wavefront challenge its detection performance.The proposed method can offer low root mean square wavefront errors and high accuracy for complex , and

Keywords： 自适应光学；波前探测；深度学习；泽尼克系数；显微成像    

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GID complex regulates the differentiation of neural stem cells by destabilizing TET2

Frontiers of Medicine doi: 10.1007/s11684-023-1007-9

Abstract: interacts with the core subunits of the glucose-induced degradation-deficient (GID) ubiquitin ligase complex, an evolutionarily conserved ubiquitin ligase complex and is ubiquitinated by itself.The protein levels of GID complex subunits increased reciprocally with TET2 level upon NSC differentiationThe silencing of the core subunits of the GID complex, including WDR26 and ARMC8, attenuated the ubiquitinationOur results illustrated that the GID complex negatively regulates TET2 protein stability, further modulates

Keywords： TET2     GID complex     neural stem cells     differentiation of neurons    

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hybrid augmented intelligence: mechanisms and applications of cognition, management, and control for complex Research Article

Fei-Yue WANG, Jianbo GUO, Guangquan BU, Jun Jason ZHANG,jun.zhang.ee@whu.edu.cn

Frontiers of Information Technology & Electronic Engineering 2022, Volume 23, Issue 8,   Pages 1142-1157 doi: 10.1631/FITEE.2100418

Abstract: mutually trustworthy (HM-KA) as the technical mechanism of hybrid augmented intelligence (HAI) based complexWe describe the historical development of complex system science and analyze the limitations of humantrustworthy HM-KA concept can provide a novel and canonical mechanism and benefit real-world practices of complex

Keywords： Complex systems     Human-machine knowledge automation     Parallel systems     Bulk power grid dispatch     Artificialintelligence    

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Footholds optimization for legged robots walking on complex terrain

Frontiers of Mechanical Engineering 2023, Volume 18, Issue 2, doi: 10.1007/s11465-022-0742-y

Abstract: novel continuous footholds optimization method for legged robots to expand their walking ability on complexslipping or tripping on the edge of obstacles, and to improve its stability and safety when walking on compleximplemented the algorithm on a hexapod robot, and verified its feasibility in a walking experiment on a complex

Keywords： footholds optimization     legged robot     complex terrain adapting     hexapod robot     locomotion control    

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Special issue: Reliability management of complex system

Frontiers of Engineering Management 2021, Volume 8, Issue 4,   Pages 477-479 doi: 10.1007/s42524-021-0175-z

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Independent cover meshless particle method for complex geotechnical engineering

Jianqiu WU, Yongchang CAI

Frontiers of Structural and Civil Engineering 2018, Volume 12, Issue 4,   Pages 515-526 doi: 10.1007/s11709-017-0428-4

Abstract: A new Independent Cover Meshless Particle (ICMP) method is proposed for the analysis of complex geotechnicalsimple formulation and a low computational cost, and is easy for the numerical analysis and modeling of complex

Keywords： meshless method     particle method     independent cover     CTM     geotechnical engineering    

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Forecast method for used number of parts and components based on complex network

LIU Fu-yun, QI Guo-ning, YANG Qing-hai

Frontiers of Mechanical Engineering 2006, Volume 1, Issue 4,   Pages 479-484 doi: 10.1007/s11465-006-0064-5

Abstract: Applying directed complex network to model the main structure of a product family, according to in-degree

Keywords： complex network     industrial     component     analytic expression     forecast    

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Cationic organobismuth complex as an effective catalyst for conversion of CO

Xiaowen ZHANG, Weili DAI, Shuangfeng YIN, Shenglian LUO, Chak-Tong AU

Frontiers of Environmental Science & Engineering 2009, Volume 3, Issue 1,   Pages 32-37 doi: 10.1007/s11783-008-0068-y

Abstract: valuable chemicals, and to exploit new applications of organobismuth compounds, cationic organobismuth complex

Keywords： cationic organobismuth complex     terminal epoxide     carbon dioxide     coupling     cyclic carbonate    

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Amino acid promoted hydrogen battery system using Mn-pincer complex for reversible CO hydrogenation to

Frontiers in Energy 2022, Volume 16, Issue 5,   Pages 697-699 doi: 10.1007/s11708-022-0843-7

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Redox reactions of iron and manganese oxides in complex systems

Jianzhi Huang, Huichun Zhang

Frontiers of Environmental Science & Engineering 2020, Volume 14, Issue 5, doi: 10.1007/s11783-020-1255-8

Abstract: . • Oxidative reactions of Mn- and Fe-oxides in complex systems were reviewed. • Reductive reaction ofFe(II)/iron oxides in complex systems was examined. • Future research on examining the redox reactivityin complex systems was suggested.Due to experimental and analytical challenges associated with complex environments, there has been aIn this Account, we primarily focused on (1) the oxidative reactivity of Mn- and Fe-oxides and (2) the

Keywords： Iron oxides     manganese oxides     reduction     oxidation     complex systems     reaction kinetics and mechanisms    

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A driving pulse edge modulation technique and its complex programming logic devices implementation

Xiao CHEN,Dong-chang QU,Yong GUO,Guo-zhu CHEN

Frontiers of Information Technology & Electronic Engineering 2015, Volume 16, Issue 12,   Pages 1088-1098 doi: 10.1631/FITEE.1500111

Abstract: This technique is used in the driving circuit based on complex programmable logic devices (CPLDs), and

Keywords： Driving pulse edge modulation     Switching voltage spike     Complex programmable logic device (CPLD)     Active    

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Title Author Date Type Operation

Autophagy and the nutritional signaling pathway

Long HE,Shabnam ESLAMFAM,Xi MA,Defa LI

Journal Article

Devising optimal integration test orders using cost–benefit analysis

Fanyi MENG, Ying WANG, Hai YU, Zhiliang ZHU,yuhai@mail.neu.edu.cn

Journal Article

Effects of parenteral nutrition with and without GH on the GH/IGF-1 axis after hepatectomy in hepatocellular

CAO Jie, LUO Shimin, LIANG Lijian, LAI Jiaming, CHEN Shanming

Journal Article

Firefly algorithm with division of roles for complex optimal scheduling

Jia Zhao, Wenping Chen, Renbin Xiao, Jun Ye,zhaojia925@163.com,chen_9731@163.com,rbxiao@hust.edu.cn,yejun68@sina.com

Journal Article

Deep learning based wavefront sensor for complex wavefront detection in adaptive optical microscopes

Shuwen Hu, Lejia Hu, Wei Gong, Zhenghan Li, Ke Si,weigong@zju.edu.cn,kesi@zju.edu.cn

Journal Article

GID complex regulates the differentiation of neural stem cells by destabilizing TET2

Journal Article

hybrid augmented intelligence: mechanisms and applications of cognition, management, and control for complex

Fei-Yue WANG, Jianbo GUO, Guangquan BU, Jun Jason ZHANG,jun.zhang.ee@whu.edu.cn

Journal Article

Footholds optimization for legged robots walking on complex terrain

Journal Article

Special issue: Reliability management of complex system

Journal Article

Independent cover meshless particle method for complex geotechnical engineering

Jianqiu WU, Yongchang CAI

Journal Article

Forecast method for used number of parts and components based on complex network

LIU Fu-yun, QI Guo-ning, YANG Qing-hai

Journal Article

Cationic organobismuth complex as an effective catalyst for conversion of CO

Xiaowen ZHANG, Weili DAI, Shuangfeng YIN, Shenglian LUO, Chak-Tong AU

Journal Article

Amino acid promoted hydrogen battery system using Mn-pincer complex for reversible CO hydrogenation to

Journal Article

Redox reactions of iron and manganese oxides in complex systems

Jianzhi Huang, Huichun Zhang

Journal Article

A driving pulse edge modulation technique and its complex programming logic devices implementation

Xiao CHEN,Dong-chang QU,Yong GUO,Guo-zhu CHEN

Journal Article